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van Hoof A, Wagner EJ (2011) A brief survey of mRNA surveillance. Trends Biochem Sci. in press.

Meaux S, Lavoie M, Gagnon J, Abou-Elela S, van Hoof A (2011) Reporter mRNAs cleaved by Rnt1p are exported and degraded in the cytoplasm. Nucleic Acids Res. in press.

Schaeffer D, and van Hoof A (2011) Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs. PNAS 108:2366-2371. [abstract]/[full text pdf]

Gao P, Pinkston KL, Nallapareddy SR, van Hoof A, Murray BE, Harvey BR (2010) The Enterococcus faecalis rnjB is required for pilin gene expression and biofilm formation. J Bact. 192:5489-5498. [abstract]/[full text pdf]

Schaeffer D, Clark A, Klauer AA, Tsanova B, and van Hoof A (2010) Functions of the cytoplasmic exosome. In: RNA exosome. T. Heick Jensen Ed. Adv Exp Med Biol. 702:79-90. [abstract]/[full text pdf]

Tsanova B, and van Hoof A(2010). Poring over exosome structure. EMBO Rep. 11:900-901. [abstract]/[full text pdf]

Jackson RN, Klauer AA, Hintze BJ, Robinson H, van Hoof A and Johnson SJ (2010). The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing. EMBO J. 29:2205-2216. [abstract]/[full text pdf]

Schaeffer D, Tsanova B, Barbas A, Pereira Reis F, Ghosh Dastidar E, Sanchez-Rotunno M, Arraiano CM, and van Hoof A (2009) The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities. Nat. Struct. Mol. Biol.16: 56-62. [abstract]/[full text pdf]

Schaeffer D, Meaux S, Clark A, and van Hoof A (2009) Determining in vivo activity of the yeast cytoplasmic exosome. Methods enzymol. [abstract]/[full text pdf]

Wilson MA, Meaux S, and van Hoof A (2008) Diverse aberrancies target yeast mRNAs to cytoplasmic mRNA surveillance pathways. BBA-GRM 1779: 550-557 [abstract]/[full text pdf]

Shyu A-B, Wilkinson MF and van Hoof A (2008) Messenger RNA regulation: to translate or to degrade. EMBO J. 27:471-481 [abstract]/[full text pdf]

S. Meaux, A. van Hoof, and K. Baker (2008) Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol. Cell 29:134-140 [abstract]/[full text pdf]

Wilson M, Meaux S, van Hoof A (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics in press. [abstract]/[full text pdf]

Grossman D, van Hoof A (2006) RNase II structure completes group portrait of 3' exoribonucleases. Nature Struct. Mol. Biol. 13:760-761. [abstract]/[full text pdf]

Meaux S, van Hoof A (2006) Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay. RNA 12:1323-1337. [abstract]/[full text pdf]

van Hoof A, Green PJ (2006) Nonsense-mediated mRNA decay in plants. In: Nonsense-mediated mRNA decay. L. E. Maquat (Ed.). [full text pdf]

Wilson M, Meaux S, Parker R, van Hoof A (2005) Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc. Natl. Acad. Sci. U.S.A. 102:10244-10249. [abstract]/[full text pdf]

van Hoof A (2005) Conserved functions of yeast genes support the Duplication, Degeneration and Complementation model for gene duplication. Genetics (in press). [abstract]/[full text pdf]/[suplementary material pdf]

Mangus DA, van Hoof A (2003) Making and Breaking the message. Genome Biology 4:346. [abstract]/[full text pdf]

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Ambro van Hoof
UT-Houston Medical School • Microbiology & Molecular Genetics
6431 Fannin Street • Houston, Texas 77030 or P.O. Box 20708 • Houston, Texas 77225
Phone: 713-500-5234• Fax: 713-500-5499 • Email:

last updated July 25, 2011 by webmaster